Unless you are short of money in the early game, or producing a product like tobacco that is in diminishing demand, I wouldn't recommend such mixed production layout, as they often lack the flexibility to increase productivity (meaning you have to change some units' type in the future and train them from level 1). Besides, some products (e.g., car, cpu, smartphone) are in great demand in the late phase of game. Even a small city usually needs at least two large factories to meet the demand, and you'd better use warehouse with storage unit to connect various factories and stores.